<<
>>

.., .., .., .. - : , , . - .: , 1991, - 496 .

., . , . , , , . - .

. .. . 2005;105(4):27-34.

. . , -: , 2006 . ISBN 5-7974-0135-5, 332

.. . - , , 2008 - 239 .

..., .. , .., .., .., .., ... . , 2010.

.., .. : , , - , , - 2001, - 2, 1, . 23-27.

.., .. , ., , 2001, 301 .

..., .., .. : , , - , - ., - 2008, - 124 .

.., .., .. . . , 3, 2009.

.., .., .., .., , .- . . . .. . 1994;94(1):9-13.

.., .. : , . //. . -2001. -.6, .3. -.4-9

.., .., . ., . . // : 2001

.. , . . ., - 2005, C. 239.

.., .. - . . , 8, 2008.

.., .., .., .., .., .., .., .. : . , 2010

. . , , 2008, . 113

Alba-Roth J, Muller OA, Schopohl J, von Werder K. Arginine stimulates growth hormone secretion by suppressing endogenous somatostatin secretion. J Clin Endocrinol Metab. 1988;67(6):1186-1189.

Alberts, B., Bray, D., Lewis, J., Raff, M., Roberts, K., Watson, J.

D. Molecular biology of the cell (3rd edition). Garland Publishing Inc, 1994

Al-Shawi R, Hafner A, Chun S, Raza S, Crutcher K, Thrasivoulou C, Simons P, Cowen T. ProNGF, Sortilin, and Age-related Neurodegeneration. Ann N Y Acad Sci. 2007 Dec;1119:208-15.

AlvarezX, Sampedro C, Cacabelos R, Linares C, Aleixandre M, Garcia-Fan- tini M, Moessler H. Reduced TNF-alpha and increased IGF-I levels in the serum of Alzheimers disease patients treated with the neurotrophic agent Cerebrolysin. Int J Neuropsychopharmacol 2009;Int J Neur:1-6.

Amara S. Oral glutamine for the prevention of chemotherapy-induced peripheral neuropathy. Ann Pharmacother. 2008;42(10):1481-5 Epub 2008 Au.

Andersson H, Lindqvist E, Olson L. Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs. Neuroreport. 1997;8(8):1813-1817.

Armengou A, Hurtado O, Leira R, Obon M, Pascual C, Moro MA, Lizasoain I, Castillo J, Davalos A. L-arginine levels in blood as a marker of nitric oxide-mediated brain damage in acute stroke: a clinical and experimental study. J Cereb Blood Flow Metab. 2003;23(8):978-984.

Babizhayev MA, Seguin MC, Gueyne J, Evstigneeva RP, Ageyeva EA, Zhel- tukhina GA.L-carnosine (beta-alanyl-L-histidine) and carcinine (beta-alanylhis- tamine) act as natural antioxidants with hydroxyl-radical-scavenging and lipidperoxidase activities.Biochem J. 1994 Dec 1;304 (Pt 2):509-16.

Bazan-Peregrino M, Gutierrez-Kobeh L, Moran J. Role of brain-derived neurotrophic factor in the protective action of N-methyl-D-aspartate in the apoptotic death of cerebellar granule neurons induced by low potassium. J Neurosci Res. 2007;85(2):332-341.

Berry HK, Brunner RL, Hunt MM, White PP. Valine, isoleucine, and leucine. A new treatment for phenylketonuria. Am J Dis Child. 1990;144(5):539-543.

Boado R.J. Brain-derived peptides increase the expression of a blood- brain barrier GLUT1 glucose transporter reporter gene.//Neurosci. Lett. -1996. -Vol.220. - P. 53-56

Boldyrev AA, Stvolinsky SL, Fedorova TN, Suslina ZA.Carnosine As a Natural Antioxidant and Geroprotector: From Molecular Mechanisms to Clinical Tri- als.Rejuvenation Res. 2009 Dec 17.

Borlongan CV, Hayashi T, Oeltgen PR, Su TP, Wang Y. Hibernation-like state induced by an opioid peptide protects against experimental stroke. BMC Biol. 2009;7:31.

Bradshaw RA, Murray-Rust J, Ibanez CF, McDonald NQ, Lapatto R, Blundell TL. Nerve growth factor: structure/function relationships. Protein Sci. 1994;3(11):1901-1913.

Branchek TA, Smith KE, Gerald C, Walker MW. Galanin receptor subtypes. Trends Pharmacol Sci. 2000;21(3):109-117.

Cervetto C, Taccola G. GABAA and strychnine-sensitive glycine receptors modulate N-methyl-D-aspartate-evoked acetylcholine release from rat spinal motoneurons: a possible role in neuroprotection. Neuroscience. 2008;154(4):1517-24 Epub 2008 M.

Cherian L, Chacko G, Goodman C, Robertson CS. Neuroprotective effects of L-arginine administration after cortical impact injury in rats: dose response and time window. J Pharmacol Exp Ther. 2003;304(2):617-623.

Clark WM, Warach SJ, Pettigrew LC, Gammans RE, Sabounjian LA. A randomized dose-response trial of citicoline in acute ischemic stroke patients. Citicoline Stroke Study Group.Neurology. 1997 Sep;49(3):671 -8.

Cline MA, Bowden CN, Calchary Wa, Layne JE. Short-term anorexigenic effects of central neuropeptide VF are associated with hypothalamic changes in chicks. J Neuroendocrinol. 2008;20(8):971-7 Epub 2008 Jun.

Cline MA, Sliwa LN. Neuropeptide VF-associated satiety involves mu and kappa but not delta subtypes of opioid receptors in chicks. Neurosci Lett. 2009;455(3):195-8 Epub 2009 Mar.

Colangelo AM, Bianco MR, Vitagliano L, Cavaliere C, Cirillo G, De Gioia L, Diana D, Colombo D, Redaelli C, Zaccaro L, Morelli G, Papa M, Sarmientos P, Alberghina L, Martegani E. A new nerve growth factor-mimetic peptide active on neuropathic pain in rats. J Neurosci. 2008;28(11):2698-2709.

Conger KA, Garcia JH, Kauffman FC, Lust WD, Murakami N, Passonneau JV. Alanine: Glutamate ratios as an index of reversibility of cerebral ischemia in gerbils. Exp Neurol. 1981;71(2):370-382.

Corbett AD, Henderson G, McKnight AT, Paterson SJ. 75 years of opioid research: the exciting but vain quest for the Holy Grail. Br J Pharmacol. 2006;147 Suppl :S153-S162.

Damulin IV, Koberskaya NN, Mkhitaryan EA. Effects of cerebrolysin on moderate cognitive impairments in cerebral vascular insufficiency (a clinical-electrophysiological study). Neurosci Behav Physiol. 2008;38(6):639-645.

De Michele M, Sancesario G, Toni D, CiuffoliA, Bernardi G, Sette G. Specific expression of galanin in the peri-infarct zone after permanent focal cerebral ischemia in the rat. Regul Pept. 2006;134(1):38-45 Epub 2006 Feb.

Deijen JB, Orlebeke JF. Effect of tyrosine on cognitive function and blood pressure under stress. Brain Res Bull. 1994;33(3):319-323.

Deijen JB, Orlebeke JF.Effect of tyrosine on cognitive function and blood pressure under stress.Brain Res Bull. 1994;33(3):319-23.

Deijen JB, Wientjes CJ, Vullinghs HF, Cloin PA, Langefeld JJ. Tyrosine improves cognitive performance and reduces blood pressure in cadets after one week of a combat training course. Brain Res Bull. 1999;48(2):203-209.

Denton M. Evolution: A Theory in Crisis. Adler & Adler, 1985. ISBN 091756152X

Domeniconi M, Hempstead BL, Chao MV. Pro-NGF secreted by astrocytes promotes motor neuron cell death. Mol Cell Neurosci. 2007 Feb;34(2):271 -9.

Domzal T, Zaleska B. Cerebrolysin in treatment of acute ischemic stroke Neurol Neurochir Pol. 1995 May-Jun;29(3):325-31.

Eriksson PS, Perfilieva E, Bj^k-Eriksson T, Alborn AM, Nordborg C, Peterson DA, Gage FH. Neurogenesis in the adult human hippocampus.Nat Med. 1998 Nov;4(11):1313-7.

Fernstrom JD. Role of precursor availability in control of monoamine biosynthesis in brain. Physiol Rev. 1983;63(2):484-546.

Fioravanti M, Yanagi M. Cytidinediphosphocholine (CDP-choline) for cognitive and behavioural disturbances associated with chronic cerebral disorders in the elderly. Cochrane Database Syst Rev. 2005;(2):CD000269.

Freeman RM, Taylor PR. Influence of histidine administration on zinc metabolism in the rat. Am J Clin Nutr. 1977;30(4):523-527.

Garmanchuk LV, Perepelitsyna EM, Sidorenko M, Makarenko AN, Kulchikov AE. [Cytoprotective effect of neuropeptides on immunocompetent cells (in vitro study)] Eksp Klin Farmakol. 2009;72(4):28-32.

Gavrilova SI, Fedorova laB, Kolykhalov IV, Odinak MM, Emelin Alu, Kashin AV, Selezneva ND, Kalyn laB, Roshchina IF. [The therapeutic potential of cerebrolysin in the preventive therapy of Alzheimers disease] Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(8):24-28.

Gladstone DJ, Black SE, Hakim AM; Heart and Stroke Foundation of Ontario Centre of Excellence in Stroke Recovery.Toward wisdom from failure: lessons from neuroprotective stroke trials and new therapeutic directions.Stroke. 2002 Aug;33(8): - P. 2123-36.

Gorovits R, Avidan N, Avisar N, Shaked I, Vardimon L. Glutamine synthetase protects against neuronal degeneration in injured retinal tissue. Proc Natl Acad Sci U S A. 1997;94(13):7024-7029.

Govorin NV, Zlova TP, Akhmetova VV, Tarasova OA. [The pathophysiological analysis of cerebrolysin therapy of children with mental developmental delay caused by ecological factors] Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(5):51 -55.

Gras G, Porcheray F, Samah B, Leone C. The glutamate-glutamine cycle as an inducible, protective face of macrophage activation. J Leukoc Biol. 2006;80(5):1067- 75 Epub 2006 A.

Grima G, Benz B, Do KQ. Glial-derived arginine, the nitric oxide precursor, protects neurons from NMDA-induced excitotoxicity. Eur J Neurosci. 2001;14(11):1762-1770.

Gromova OA, Tretiakov VE, Moshkovskii SA, GusevEI, Nikonov AA, Valkova LA, Glibin AS, Kataev AS. An oligopeptide membrane fraction of cerebrolysin. Zh NevrolPsikhiatrIm S S Korsakova. 2006;106(7):68-70.

Gusev EI, Skvortsova VI, Dambinova SA, Raevskiy KS, Alekseev AA, Bashkatova VG, Kovalenko AV, Kudrin VS, Yakovleva EV. Neuroprotective effects of glycine for therapy of acute ischaemic stroke. Cerebrovasc Dis. 2000;10(1):49-60.

Gutmann B, Hutter-Paier B, Skofitsch G, Windisch M, Gmeinbauer R.In vitro models of brain ischemia: the peptidergic drug cerebrolysin protects cultured chick cortical neurons from cell death.Neurotox Res. 2002 Feb;4(1): - P. 59-65.

Hao S, Avraham Y, Bonne O, Berry EM. Separation-induced body weight loss, impairment in alternation behavior, and autonomic tone: effects of tyrosine. Pharmacol Biochem Behav. 2001;68(2):273-281.

Hawes JJ, Narasimhaiah R, Picciotto MR. Galanin and galanin-like peptide modulate neurite outgrowth via protein kinase C-mediated activation of extracellular signal-related kinase. Eur J Neurosci. 2006;23(11):2937-2946.

Hayashi T, Su TP. Chronic [D-Ala2, D-Leu5]enkephalin treatment increases the nerve growth factor in adult mouse brain. Eur J Pharmacol. 2003;464(2-3):237-239.

Hazell AS. Excitotoxic mechanisms in stroke: an update of concepts and treatment strategies. Neurochem Int. 2007;50:941-953.

Hong-Ping G, Bao-Shan KU. Neuroprotective effect of L-lysine monohydrochloride on acute iterative anoxia in rats with quantitative analysis of electro- corticogram. Life Sci. 1999;65(2):PL19-PL25.

Huang EJ, Reichardt LF. Trk receptors: roles in neuronal signal transduction. Annu Rev Biochem. 2003;72:609-642.

Huffner2001A randomized, double-blind, placebo-controlled trial with cerebrolysin in acute ischemic stroke//Cerebrovasc Dis 2001; 11 (suppl 4): 1-128

Hughes P, Beilharz E, Gluckman P, Dragunow M. Brain-derived neurotrophic factor is induced as an immediate early gene following N-methyl-D-aspartate receptor activation. Neuroscience. 1993;57(2):319-328.

Ibanez CF. Jekyll-Hyde neurotrophins: the story of proNGF. Trends Neuro- sci. 2002;25(6):284-286.

Ignarro LJ. Nitric oxide. A novel signal transduction mechanism for transcellular communication. Hypertension. 1990;16(5):477-483.

Jayalakshmi K, Sairam M, Singh SB, Sharma SK, Ilavazhagan G, Banerjee PK. Neuroprotective effect of N-acetyl cysteine on hypoxia-induced oxidative stress in primary hippocampal culture. Brain Res. 2005;1046(1 -2):97-104.

Jean YY, Lercher LD, Dreyfus CF. Glutamate elicits release of BDNF from basal forebrain astrocytes in a process dependent on metabotropic receptors and the PLC pathway. Neuron Glia Biol. 2008;4(1):35-42.

Jezova D, Tokarev D, Rusnak M. Endogenous excitatory amino acids are involved in stress-induced adrenocorticotropin and catecholamine release. Neuroendocrinology. 1995;62(4):326-332.

Jezovô D, Tokarev D, Rusnôk M.Endogenous excitatory amino acids are in - volved in stress-induced adrenocorticotropin and catecholamine release.Neu- roendocrinology. 1995 Oct;62(4):326-32.

Kagiyama T, Glushakov AV, Sumners C, Roose B, Dennis DM, Phillips MI, Ozcan MS, Seubert CN, Martynyuk AE. Neuroprotective action of halogenated derivatives of L-phenylalanine. Stroke. 2004;35(5):1192-6 Epub 2004 Ap.

Kenney JL, Carlberg KA. The effect of choline and myo-inositol on liver and carcass fat levels in aerobically trained rats. Int J Sports Med. 1995;16(2):114-116.

Klebanov GI, Teselkin YuO, Babenkova IV, Lyubitsky OB, Rebrova OYu, Boldyrev AA, Vladimirov YuA.Effect of carnosine and its components on free- radical reactions.Membr Cell Biol. 1998;12(1):89-99.

Koppi S, Barolin GS. Hemodilution therapy with neuron metabolism specific therapy in ischemic stroke--encouraging results of a comparative study Wien Med Wochenschr. 1996;146(3):41 -8.

Kretschmer BD, Schmidt WJ, Kostrzewa RM, Marschitz-Herra M. Amino acids in neurobiology: neuroprotective and neurotoxic aspects of amino acids involved in neurotransmission and neuromodulation -- general introduction. Amino Acids. 2002;23(1 -3):1 - 7.

Kulchikov AE, Makarenko AN. [Effects of neuropeptides on interferon production in vitro] Patol Fiziol Eksp Ter. 2008;(2):11-12.

Kulchikov AE, Makarenko AN. [Neuroimmunocorrection therapy for the prophylaxis of infectious complications in acute stroke patients] Eksp Klin Farmakol. 2008;71(6):34-38.

Kvrivishvili G. Glycine and neuroprotective effect of hypothermia in hypoxic- ischemic brain damage. Neuroreport. 2002;13(16):1995-2000.

Ladurner G., Kalvach P., Moessler H.; Cerebrolysin Study Group. Neuroprotective treatment with cerebrolysin in patients with acute stroke: a randomised controlled trial. J Neural Transm. 2005 Mar;112(3): - P. 415-28.

Lang R, Gundlach AL, Kofler B. The galanin peptide family: receptor pharmacology, pleiotropic biological actions, and implications in health and disease. Pharmacol Ther. 2007;115(2):177-207 Epub 2007 M.

Lee J, Duan W, Mattson MP. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J Neurochem. 2002;82:1367-1375. Lerner JT, Sankar R, Mazarati AM. Galanin and epilepsy. Cell Mol Life Sci. 2008;65(12):1864-1871.

Leuzzi V, Fois D, Carducci C, Antonozzi I, Trasimeni G. Neuropsychological and neuroradiological (MRI) variations during phenylalanine load: protective effect of valine, leucine, and isoleucine supplementation. J Child Neurol. 1997;12(5):338-340.

Lombardi V., Ccabelos R., Perez P. et al. Cerebrolysin improves memory performance and the brain bioelectrical activity pattern in elderly humans. // Neurobiol. Aging. -2000. -Vol.21, N.1S. -P.S167

Lu X, Barr AM, Kinney JW, Sanna P, Conti B, Behrens MM, Bartfai T. A role for galanin in antidepressant actions with a focus on the dorsal raphe nucleus. Proc Natl Acad Sci U S A. 2005;102(3):874-9 Epub 2005 Jan.

Lucus D.R., Newhouse J.P. Arch. OphihalmoL 58, - 1957, - P. 193-201.

Lundstrom L, Elmquist A, Bartfai T, Langel U. Galanin and its receptors in neurological disorders. Neuromolecular Med. 2005;7(1-2):157-180.

Magill RA, Waters WF, Bray GA, Volaufova J, Smith SR, Lieberman HR, McNevin N, Ryan DH. Effects of tyrosine, phentermine, caffeine D-amphetamine, and placebo on cognitive and motor performance deficits during sleep deprivation. Nutr Neurosci. 2003;6(4):237-246.

Maisonpierre PC, Belluscio L, Squinto S, Ip NY, Furth ME, Lindsay RM, Yancopoulos GD. Neurotrophin-3: a neurotrophic factor related to NGF and BDNF. Science. 1990,247(4949 P:1446-1451.

Maksimova Mlu, Briukhov VV, Timerbaeva SL, Kistenev BA, Rebrova Olu, Suslina ZA. [Effectiveness of cerebrolysin in hypertensive supratentorial intracranial hemorrhages: results of a randomized triple blind placebo-controled study] Zh Nevrol Psikhiatr Im S S Korsakova. 2009;109(1):20-26.

Marini AM, et al. Activity-dependent release of brain-derived neurotrophic factor underlies the neuroprotective effect of N-methyl-D-aspartate. J Biol Chem. 1998;273:29394-29399.

Marini AM. Preconditioning and neurotrophins: a model for brain adaptation to seizures, ischemia and other stressful stimuli. Amino Acids. 2007;32:299-304.

Martinez-Orgado J, Fernandez-Frutos B, Gonzalez R, Fernandez-Lopez D, Uriguen L, Romero E, Moro M, Bonet B, Viveros MP. Neuroprotective effect of L-arginine in a newborn rat model of acute severe asphyxia. Biol Neonate. 2005;88(4):291 -8

Masliah E, Armasolo F, Veinbergs I, Mallory M, Samuel W. Cerebrolysin ameliorates performance deficits, and neuronal damage in apolipoprotein E- deficient mice. Pharmacol Biochem Behav. 1999 Feb;62(2): - P. 239-45.

Mattson MP. Calcium and free radicals: mediators of neurotrophic factor and excitatory transmitter-regulated developmental plasticity and cell death. Perspect Dev Neurobiol. 1996;3:79-91.

Mattson MP. Excitotoxic and excitoprotective mechanisms: abundant targets for the prevention and treatment of neurodegenerative disorders. Neuromolecular Med. 2003;3:65-94.

Mattson MP. Glutamate and neurotrophic factors in neuronal plasticity and disease. Ann N Y Acad Sci. 2008,1144:97-112.

Moschou M, Kosmidis EK, Kaloyianni M, Geronikaki A, Dabarakis N, Theophilidis G. In vitro assessment of the neurotoxic and neuroprotective effects of N-acetyl-L-cysteine (NAC) on the rat sciatic nerve fibers. Toxicol In Vitro. 2008;22(1):267-74.

Mothet JP, Parent AT, Wolosker H, Brady RO Jr, Linden DJ, Ferris CD, Rogawski MA, Snyder SH. D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor. Proc Natl Acad Sci US A. 2000;97(9):4926-4931.

Muresanu DF, Alvarez XA, Moessler H, Buia M, Stan A, Pintea D, Moldovan F, Popescu BO. A pilot study to evaluate the effects of Cerebrolysin on cognition and qEEG in vascular dementia: cognitive improvement correlates with qEEG acceleration. J Neurol Sci. 2008;267(1-2):112-9 Epub 2007 Nov.

Muresanu DF, Rainer M, Moessler H.Improved global function and activities of daily living in patients with AD: a placebo-controlled clinical study with the neurotrophic agent Cerebrolysin.J Neural Transm Suppl. 2002,(62): - P. 277-85

Nagai K, Suda T. Realization of spontaneous healing function by carnosine. Methods Find Exp Clin Pharmacol. 1988;10(8):497-507.

Neri DF, Wiegmann D, Stanny RR, Shappell SA, McCardie A, McKay DL. The effects of tyrosine on cognitive performance during extended wakefulness. Aviat Space Environ Med. 1995;66(4):313-319.

Oliff HS, et al. Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus. Mol Brain Res. 1998;61:147- 153.

OlneyJ.W. Science - 1969, - 164, - P. 719-721.

Petock JM, Torshin IY, Weber IT, Harrison RW. Analysis of protein structures reveals regions of rare backbone conformation at functional sites. Proteins. 2003;53(4):872-879.

Porzionato A, Macchi V, ParentiA, De Caro R. Trophic factors in the carotid body. Int Rev Cell Mol Biol. 2008;269:1-58.

Prospero-Garcia O, Mendez-Diaz M. The role of neuropeptides in sleep modulation. Drug News Perspect. 2004;17(8):518-522.

Ramakrishnan S., Sulochana K.N., Selvaraj T., Abdul Rahim A., Lakshmi M., Arunagiri K. Smoking of beedies and cataract: cadmium and vitamin C in the lens and blood //Br J Ophthalmol, - 1995, - N 79, - P. 202-206.

Ramonet D, Rodriguez MJ, Fredriksson K, Bernal F, Mahy N. In vivo neuroprotective adaptation of the glutamate/glutamine cycle to neuronal death. Hippocampus. 2004;14(5):586-594.

Rasmussen DD, Ishizuka B, Quigley ME, Yen SS. Effects of tyrosine and tryptophan ingestion on plasma catecholamine and 3,4-dihydroxyphenylacetic acid concentrations. J Clin Endocrinol Metab. 1983;57(4):760-763.

Reinstein DK, Lehnert H, Wurtman RJ. Dietary tyrosine suppresses the rise in plasma corticosterone following acute stress in rats. Life Sci. 1985;37(23):2157-2163.

Saransaari P, Oja SS. Beta-alanine release from the adult and developing hippocampus is enhanced by ionotropic glutamate receptor agonists and celldamaging conditions. Neurochem Res. 1999;24(3):407-414.

Schaechter JD, Wurtman RJ. Serotonin release varies with brain tryptophan levels. Brain Res. 1990;532(1-2):203-210.

Schwab M., Bauer R., Zweiner U. Physiological effects and brain protection by hypothermia and Cerebrolysin after moderate forebrain ischemia in rats. //Exp. Toxicol. Pathol. -1997. -Vol.49. -P.105-116

Schwendt M, Jezova D. Gene expression of NMDA receptor subunits in rat adrenals under basal and stress conditions. J Physiol Pharmacol. 2001;52(4 Pt 2):719-727.

Serkina EV, Gromova OA, Torshin IIu, Sotnikova NIu, Nikonov AA. [Cerebrolysin alleviates perinatal CNS disorders through the autoimmune modulation and antioxidant protection] Zh Nevrol Psikhiatr Im S S Korsakova. 2008;108(11):62-66.

Sharma HS. Neurobiology of the CNS injury and repair: New roles of amino acids, growth factors and neuropeptides -- introduction. Amino Acids. 2002;23(1-3):217-219.

Skvortsova VI, Raevskii KS, Kovalenko AV, Kudrin VS, Malikova LA, Sokolov MA, Alekseev AA, Gusev EI. Levels of neurotransmitter amino acids in the cerebrospinal fluid of patients with acute ischemic insult. Neurosci Behav Physiol. 2000;30(5):491 -495.

Sprince H, Parker CM, Smith GG, Gonzales LJ. Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking. Agents Actions. 1975;5(2):164-173.

Sprince H, Parker CM, Smith GG, Gonzales LJ.Protective action of ascorbic acid and sulfur compounds against acetaldehyde toxicity: implications in alcoholism and smoking.Agents Actions. 1975 May;5(2):164-73.

Stone TW, Forrest CM, Mackay GM, Stoy N, Darlington LG. Tryptophan, adenosine, neurodegeneration and neuroprotection. Metab Brain Dis. 2007;22(3-4):337-352.

Stubblefield MD, Vahdat LT, Balmaceda CM, Troxel AB, Hesdorffer CS, Gooch CL. Glutamine as a neuroprotective agent in high-dose paclitaxel-induced peripheral neuropathy: a clinical and electrophysiologic study. Clin Oncol (R Coll Radiol). 2005;17(4):271-276.

Su AI, Wiltshire T, Batalov S, Lapp H, Ching KA, Block D, Zhang J, Soden R, Hayakawa M, Kreiman G, Cooke MP, Walker JR, Hogenesch JB. A gene atlas of the mouse and human protein-encoding transcriptomes. Proc Natl Acad Sci U S A. 2004;101(16):6062-7.

Suarez V, Guntinas-Lichius O, Streppel M, Ingorokva S, Grosheva M, Neiss WF, Angelov DN, Klimaschewski L. The axotomy-induced neuropeptides galanin and pituitary adenylate cyclase-activating peptide promote axonal sprouting of primary afferent and cranial motor neurones. Eur J Neurosci. 2006;24(6):1555-1564.

Suzuki M, et al. Glutamate enhances proliferation and neurogenesis in human neural progenitor cell cultures derived from the fetal cortex. Eur J Neurosci. 2006;24:645-653.

Tang SC, Arumugam TV, Cutler RG, Jo DG, Magnus T, Chan SL, Mughal MR, Telljohann RS, Nassar M, OuyangX, Calderan A, Ruzza P, Guiotto A, Mattson MP. Neuroprotective actions of a histidine analogue in models of ischemic stroke. J Neurochem. 2007;101(3):729-36 Epub 2007 Ja.

Tatebayashi Y., Lee M.H., Iqbal K., Grundke-Iqbal I. The peptidergic antidementia drug Cerebrolysin increases neurogenesis in the adult rat dentate gyrus and improves spatial learning and memory. //Neurobiol. Aging. -2000. -Vol.21, N.1S. - P.S42

Tchantchou F, Graves M, Falcone D, Shea TB. S-adenosylmethionine mediates glutathione efficacy by increasing glutathione S-transferase activity: implications for S-adenosyl methionine as a neuroprotective dietary supplement. J Alzheimers Dis. 2008;14(3):323-328.

Tchantchou F, Graves M, Ortiz D, Rogers E, Shea TB. Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge: relevance to age-related neurodegeneration. Neuromolecular Med. 2004;6(2-3):93-103.

Temiz C, Tun K, Ugur HC, Dempsey RJ, Egemen N. L-arginine in focal cerebral ischemia. Neurol Res. 2003;25(5):465-470.

Tobi D, Bahar I. Recruitment of rare 3-grams at functional sites: is this a mechanism for increasing enzyme specificity? BMC Bioinformatics. 2007;8:226.

Torshin I.Yu. Bioinformatics in the post-genomic era: physiology and medicine. Nova Biomedical Books, NY, USA (2007), ISBN: 1600217524, pp1-20.

Torshin I.Yu. Bioinformatics in the post-genomic era: sensing the change from molecular genetics to personalized medicine. Nova Biomedical Books, NY, USA, 2009, In Bioinformatics in the Post-Genomic Era series, ISBN: 978-1-60692-217-0

Torshin I.Yu., Gromova O.A. Magnesium and pyridoxine: fundamental studies and clinical practice. Nova Science, NY, 2009, ISBN-10: 1-60741-704-9.

Tuncer MC, Hatipoglu ES, Ozturk H, Kervancioglu P, Buyukbayram H. The effects of L-arginine on neurological function, histopathology, and expression of hypoxia-inducible factor-1 alpha following spinal cord ischemia in rats. Eur Surg Res. 2005;37(6):323-329.

Unsicker K, Stogbauer F. Screening of adrenal medullary neuropeptides for putative neurotrophic effects. Int J DevNeurosci. 1992;10(2):171-179.

Unsicker K, S^gbauer F.Screening of adrenal medullary neuropeptides for putative neurotrophic effects.Int J Dev Neurosci. 1992 Apr;10(2):171 -9.

Veinbergs I., Mante M., Mallory M., Masliah E. Neurotrophic effects of Cerebrolysin in animal models of excitotoxicity.// J Neural Transm Suppl. - 2000; 59: - P. 273-80.

Vole D. 1998 Therapeutic Effects of Cerebrolysin in Stroke Patients during Rehabilitation //EuroRehab 3-4

Vrontakis ME. Galanin: a biologically active peptide. Curr Drug Targets CNS Neurol Disord. 2002;1(6):531-541.

Wang GH, Jiang ZL, Fan XJ, Zhang L, Li X, Ke KF. Neuroprotective effect of taurine against focal cerebral ischemia in rats possibly mediated by activation of both GABAA and glycine receptors. Neuropharmacology. 2007;52(5):1199-209 Epub 2007.

Wang M, Yang Y, Dong Z, Cao J, Xu L. NR2B-containing N-methyl-D-as- partate subtype glutamate receptors regulate the acute stress effect on hippocampal long-term potentiation/long-term depression in vivo. Neuroreport. 2006;17(12):1343-1346.

Watkins JC, Jane DE. The glutamate story. Br J Pharmacol. 2006;147 Suppl :S100-S108.

Wiesmann C, Ultsch MH, Bass SH, de Vos AM.Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor. Nature. 1999 Sep 9;401(6749):184-8.

White BC, Sullivan JM, DeGracia DJ, ONeil BJ, Neumar RW, Grossman LI, Rafols JA, Krause GS.Brain ischemia and reperfusion: molecular mechanisms of neuronal injury.J Neurol Sci. 2000 Oct 1;179(S 1 -2): - P. 1 -33.

Wolosker H, Panizzutti R, De Miranda J. Neurobiology through the looking-glass: D-serine as a new glial-derived transmitter. Neurochem Int. 2002;41(5):327-332.

Wong GK, Zhu XL, Poon WS. Beneficial effect of cerebrolysin on moderate and severe head injury patients: result of a cohort study. Acta Neurochir Suppl. 2005;95:59-60.

Wood AM, Bristow DR. N-methyl-D-aspartate receptor desensitisation is neuroprotective by inhibiting glutamate-induced apoptotic-like death. J Neuro- chem. 1998;70(2):677-687.

Wronski R., Tompa P., Hutter-Paier B., Crailsheim K., Friedrich P., Windisch M. Inhibitory effect of a brain derived peptide preparation on the Ca2+-depen- dentprotease, calpain. J Neural Transm. 2000;107(2): - P. 145-57

Wurtman RJ, Anton-Tay F. The mammalian pineal as a neuroendocrine transducer. Recent Prog Horm Res. 1969;25:493-522.

Wynick D, Thompson SW, McMahon SB. The role of galanin as a multifunctional neuropeptide in the nervous system. Curr Opin Pharmacol. 2001;1(1):73-77.

Yamada N, Katsuura G, Tatsuno I, Kawahara S, Ebihara K, Saito Y, Nakao K. Orexins increase mRNA expressions of neurotrophin-3 in rat primary cortical neuron cultures. Neurosci Lett. 2009;450(2):132-5 Epub 2008 Nov.

Yamagata K, Shoji Y, Terashima T, Yokogoshi H. Glutamate reduces secretion of l-serine in astrocytes isolated from stroke-prone spontaneously hypertensive rats. Neuroscience. 2006;143(3):729-37 Epub 2006 Oc.

Zhang H, Torregrossa MM, Jutkiewicz EM, Shi YG, Rice KC, Woods JH, Watson SJ, Ko MC. Endogenous opioids upregulate brain-derived neurotrophic factor mRNA through delta- and micro-opioid receptors independent of antidepressant-like effects. Eur J Neurosci. 2006;23(4):984-994.

<< | >>
: . ., . .. - 61 . - .: , 2012- 747 .. 2012

:

  1. .
  2. :
  3. :
- - - - - - - - - -
- - - - - - - - - - - - -