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CHLORTETRACYCLINI HYDROCHLORIDUM

( )

. C22H23CIN2CVHCI. . 515,4.

.

I II I II

6286

-6--1,11--2- ; [ 4S-(4,4,5,6,12)]-7--4-()-1,4,4,5, 5,6,11,12- -3,6,10,12,12--6--1,11-- -2- ; per.

CAS 64-72-2.

. .

. 100 250 (~750 /) ; , .

. .

. , .

. , , , .

. . , .

. 900 ME 1

. , (. 1, . 92), , : 25 1 50 2,5 47,5 (0,1 /) , pH 7 (^ 100 /) . 70 90 , . 200 2 , 2 1 , 25 (0,1 /) ,

pH 7 ( 100 /) , . . 1 3 , () 0,50 1 , () 0,50 1 () ^ 0,50 1 , 0.50 - 1 0,50 1 . , ( 260 /) (365 ). , , , , . , 3 .

. 10 10 pH 7,6 , 1 100 (365 ); .

. 1 2 (1760 /) ; - , 1 .

. 0,05 / , (. 1, . 129).

. 0,125 25,0 30 . 25 ; 15= 235 250.

. 0,5 3, (. 1, . 136); (. 1 - 137); 50 /.

. 5,0 /.

. 60 ( 0,6 ( 5 . .) - 3 ; 20 /.

PH . pH - 10 / 2,33,3.

. 10 100 (0,5 /) . 10 100 (0,5 /) . 10 25 200 ' ' 8 . , . , , 1 274 ; 0,70 0,76.

. , (. 1, . 165), (a) Bacillus putnilus ( NCTC 8241 14884) - , 1 pH 6,56,6, pH 4,5 , - ( 220 /) 3539 () Bacillus cereus ( 11778) -, 1 pH 5,96,0, pH 4,5 , ( 0,050,2 /) 29 33. , ( = 0,95) 95 105% . ( = 0,95) 900 ME 1 .

. , .

. , (. 1, . 176), 0,5 , , 2 /.

. , (. 1, . 176), 1 1 , 5 1 .

. (. 1, . 172), .

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: . . 3. . .1990. 1990

CHLORTETRACYCLINI HYDROCHLORIDUM :

  1. BLEOMYCINI HYDROCHLORIDUM. . ( ).
  2. AMILORIDI HYDROCHLORIDUM. .
  3. PROCARBAZINI HYDROCHLORIDUM
  4. OXYTETRACYCLINI HYDROCHLORIDUM
  5. DOXORUBICINI HYDROCHLORIDUM
  6. BIPERIDENI HYDROCHLORIDUM.
  7. LOPERAMIDI HYDROCHLORIDUM
  8. EPHEDRINI HYDROCHLORIDUM
  9. TRIHEXYPHENIDYL! HYDROCHLORIDUM
  10. THIAMINI HYDROCHLORIDUM
  11. NOSCAPINI HYDROCHLORIDUM
  12. METOCLOPRAMIDI HYDROCHLORIDUM
  13. PETHIDINI HYDROCHLORIDUM
  14. SPECTINOMYCINI HYDROCHLORIDUM
  15. PROMETHAZINI HYDROCHLORIDUM
  16. HYDRALAZINI HYDROCHLORIDUM
  17. NALOXONIHYDROCHLORIDUM
  18. DOPAIWINI HYDROCHLOR1DHM
  19. DIPHENOXYLATI HYDROCHLOR1DUM
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