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OXYTETRACYCLINI HYDROCHLORIDUM

( )

. C22H24N2O9 HCI.

. 496,9.

.

. (4S,4a/?,5S,5a/?,6S,12aS)-4-(flHMemri- )-1,4,4,5,5,6,11,12--3,5,6,10,12,12 - - -6--1,11--2- ; [4S- (4,4,5,5,,12) ]-4- () -1,4,4,5,5, 6,11,12--3,5,6,10,12,12 - -6--1,11-- -2- ; per. CAS 2058-46-0.

. .

. 2 45 (~750 /) ; .

. .

. , .

. , , , .

. . , . - .

pH 2 .

. 870 ME 1 .

. , (. 1, . 92), , : 25 1 50 2,5 47,5 (0,1 /) , pH 7 (100 /) . 7090 , . 200 2 - , 2 1 , 25 (0,1 /) , pH 7 (- 100 /) , . 1 3 , () 0,50 1 , () 0,50 1 () 0,50 1 , 0,50 1 0,50 1 . , (~260 /) (365 ). , , , , . , 3 . . 1 2 (~1760 /) ; - , 0,1 .

. 0,05 / , (.

1, . 129).

. 0,25 (0,1 /) , 25 , 60 . : [aJjc=OT 188 200.

. 5,0 /.

. . (. 1, . 155), 0,25 ; 20 /.

pH . pH 10 / 2,03,0.

. 20 / (0,1 /) 230 400 2 268 353 . 1 353 0,54 0,58.

. 2,0 / 1 (1 /) 99 1 430 1 ; 0,50.

10 / 1 (1 /) 99 1 490 1 ; 0,20.

. , (. 1, . 165), () Bacillus pumilus ( NCTC 8241 14884) -, 1 pH 6,56,6, pH 4,5 , - ( 2 20 /) 3739 , () Bacillus cereus ( 11778) -, 1 pH 5,96,0, pH 4,5 , ( 0,52 ME)

Η33 . , ( = 0,95) 95 105% . ( = 0,95) 870 ME 1 .

. , (. 1, . 176), 0,5 , , 2 1 .

. , (. 1, . 176), 1 5 , , 1 1 .

. , (. 1, . 172), .

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: . . 3. . .1990. 1990

OXYTETRACYCLINI HYDROCHLORIDUM :

  1. OXYTETRACYCLINI DIHYDRAS
  2. BLEOMYCINI HYDROCHLORIDUM. . ( ).
  3. AMILORIDI HYDROCHLORIDUM. .
  4. PROCARBAZINI HYDROCHLORIDUM
  5. DOXORUBICINI HYDROCHLORIDUM
  6. BIPERIDENI HYDROCHLORIDUM.
  7. LOPERAMIDI HYDROCHLORIDUM
  8. EPHEDRINI HYDROCHLORIDUM
  9. TRIHEXYPHENIDYL! HYDROCHLORIDUM
  10. THIAMINI HYDROCHLORIDUM
  11. NOSCAPINI HYDROCHLORIDUM
  12. CHLORTETRACYCLINI HYDROCHLORIDUM
  13. METOCLOPRAMIDI HYDROCHLORIDUM
  14. PETHIDINI HYDROCHLORIDUM
  15. SPECTINOMYCINI HYDROCHLORIDUM
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