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1.11. , 㳿, - ,

, 24- (min) (Emin) .

(Cmax) , (Emax). , . , , , .

: retard (), CD - controlled delivery ( ), CR controlled release ( ), CC - coat core ( ), LA long-acting (), Lp liberation prolongee ( ), SRO sustained release oral ( ).

㳿 - (retardo - , ) ' 1970-1980- ., , , , . г , , 䳺 㳿 OROS (Oral Osmotic). ϳ (Geomatrix, Skye Pharma), ' ' . , , 糿 . ϳ ', , , , , , .

(SODAS, Elan) . 12 , , . , , , , .

-, , , .

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: . . , . . , ... ˲Ͳ ֲ. ϳ ̳ - 2013. 2013

1.11. , 㳿, - , :

  1. 6.12. , , - ,
  2. 6.12. , , - ,
  3. 7.10. , , - ,
  4. 4.10. 㳿
  5. 4.10. 㳿
  6. 8.7.
  7. 9.8. , 㳿
  8. 3.9. -
  9. 7.3. - ,
  10. 8.4. . .
  11. 6.3. .
  12. 9.3. , . .
  13. 10.6. 㳿
  14. 5.3.
  15. C01D. IJ, IJò
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- - - - - - - - - - - - -